CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25289
Family Name Glucose-dependent insulinotropic receptor ligand propan-2-yl 4-[5-ethyl-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00473731 Functional Category Bioactive
Superfamily Glucose-dependent insulinotropic receptor Binder Superfamily 2
Class Class 380

Cousin Family NamesSeedsMembers
Glucose-dependent insulinotropic receptor ligand propan-2-yl 4... 2 54
Glucose-dependent insulinotropic receptor ligand 4-[1-(4-Metha... 9 22
Glucose-dependent insulinotropic receptor ligand tert-butyl (1... 3 14
Glucose-dependent insulinotropic receptor ligand S-propan-2-yl... 1 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 1
Glucose-dependent insulinotropic receptor ligand 6-[[(1S,5S)-8... 1 0
Glucose-dependent insulinotropic receptor ligand propan-2-yl 4... 1 3


External ID

Functional Category

Molecule Name

CFAMM00473732 CHEMBL1951029 Bioactive propan-2-yl 4-[5-cyclopropyl-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate
CFAMM00473731 CHEMBL1951028 Bioactive propan-2-yl 4-[5-ethyl-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate
CFAMM00473735 CHEMBL1951034 Bioactive propan-2-yl 4-[6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]-5-propan-2-yloxypyrimidin-4-yl]oxypiperidine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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