CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2530
Family Name 5-hydroxytryptamine receptor 6 ligand SureCN5502542 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00335132 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 Binder Superfamily 3
Class Class 44

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Phospholipase A2 Inhibitor Quinacrine Family 13 95
DNA Binder Elliptinium Acetate Family 11 116
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 3
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-m... 2 12
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 1
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Cannabinoid receptor 2 ligand AGN-PC-09M5M9 family 1 0
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Progesterone receptor and Androgen receptor ligand AGN-PC-04QD... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Integrase inhibitor (Z)-4-[1-[(4-fluorophenyl)methyl]-5-methox... 1 0
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
5-hydroxytryptamine receptor 6 ligand 9-(4-methoxyphenyl)sulfo... 1 0
5-hydroxytryptamine receptor 6 ligand 1-(2-bromo-4-methoxyphen... 2 1
Acetylcholinesterase and Cholinesterase inhibitor N-[5-[(6-chl... 4 2
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 1 2
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-075BWR family 1 1
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 14 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335133 CHEMBL2165550 Bioactive 9-(2-chlorophenyl)sulfonyl-6-methoxy-N,N-dimethyl-1,2,3,4-tetrahydrocarbazol-3-amine
CFAMM00335132 CHEMBL72574 Bioactive SureCN5502542
CFAMM00335131 CHEMBL368746 Bioactive AGN-PC-075ASI
CFAMM00335129 CHEMBL127636 Bioactive SureCN5501752

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543