CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25305
Family Name Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chlorophenyl)-2-[(2Z)-2-pyrrol-2-ylidene-3H-benzimidazol-1-yl]acetamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00473793 Functional Category Bioactive
Superfamily Inosine-5'-monophosphate dehydrogenase and Prelamin-A/C Binder Superfamily
Class Class 4

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
SB989 family 17 91
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Inosine-5'-monophosphate dehydrogenase and Nuclear receptor RO... 2 9
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 3 10
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 2 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 5 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
B1 bradykinin receptor ligand AGN-PC-077LWO family 2 0
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 6 0
Sodium channel protein type 9 subunit alpha and Sodium channel... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473793 CHEMBL1957260 Bioactive N-(4-chlorophenyl)-2-[(2Z)-2-pyrrol-2-ylidene-3H-benzimidazol-1-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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