CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25315
Family Name Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 ligand AGN-PC-075X5Z family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00473838 Functional Category Bioactive
Superfamily Cytochrome P450 1A2 and Nonstructural protein 1 Binder Superfamily
Class Class 1981

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Metabotropic glutamate receptor 5 Ligand 2-methyl-4-(pyridin-3... 10 35
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(n-o... 3 12
Motilin receptor and Cytochrome P450 2D6 ligand 7-[[6-(4-chlor... 2 1
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
Substance-K receptor and Cytochrome P450 2D6 ligand 158848-32-... 4 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00473839 CHEMBL196343 Bioactive AGN-PC-075X5T
CFAMM00473838 CHEMBL196054 Bioactive AGN-PC-075X5Z

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27255 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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