CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2532
Family Name D(2) dopamine receptor ligand 2-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-hydroxy-6-methoxybenzamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00335138 Functional Category Bioactive
Superfamily D(2) dopamine receptor Ligand Epidepride Superfamily
Class Class 322

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Nemonapride Family 70 283
D(2) dopamine receptor Ligand Sulpiride Family 7 38
D(2) dopamine receptor Ligand Remoxipride Family 12 84
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Insulin receptor Ligand Meglitinides Family 9 25
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
5-hydroxytryptamine receptor 3A Ligand KB-6806 Family 12 11
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Histamine H3 receptor Ligand A-349821 Family 49 228
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
D(2) dopamine receptor Ligand Epidepride Family 31 66
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[(3... 2 11
D(2) dopamine receptor ligand (E)-2,3-dihydroxybut-2-enedioic ... 6 10
D(2) dopamine receptor ligand 2-bromo-3-chloro-N-[[(2S)-1-ethy... 1 1
D(2) dopamine receptor ligand 2-bromo-N-[[(2S)-1-ethylpyrrolid... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Pol polyprotein inhibitor CHEMBL305466 family 4 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 14 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Sigma non-opioid intracellular receptor 1 and D(3) dopamine re... 26 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
Melanin-concentrating hormone receptor 1 ligand N-methyl-N-[(3... 2 2
Dipeptidyl peptidase 4 inhibitor SureCN5777647 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335138 CHEMBL1276560 Bioactive 2-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-hydroxy-6-methoxybenzamide
CFAMM00335137 CHEMBL1276375 Bioactive 2-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-6-methoxybenzamide
CFAMM00335136 CHEMBL1276615 Bioactive 2-chloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-hydroxy-6-methoxy-3-propylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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