CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25348
Family Name Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family
No. of Seeds 9 No. of Other Members 12
Family Centroid CFAMM00473939 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase and Glutamate receptor ionotropic, NMDA 1 Binder Superfamily
Class Class 4064

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Hemagglutinin Inhibitor Arbidol Family 1 4
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Renin inhibitor SureCN1144364 family 3 15
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 1
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 3 12
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 1 8
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1


External ID

Functional Category

Molecule Name

CFAMM00473943 CHEMBL484277 Bioactive SureCN4558769
CFAMM00473929 CHEMBL484482 Bioactive ethyl 2-[(4-bromophenyl)methyl]-5-hydroxy-1H-benzo[g]indole-3-carboxylate
CFAMM00473942 CHEMBL490461 Bioactive SureCN530099
CFAMM00473933 CHEMBL519150 Bioactive ethyl 2-(4-chlorophenyl)-5-hydroxy-1H-benzo[g]indole-3-carboxylate
CFAMM00473946 CHEMBL520798 Bioactive ethyl 2-[2-(4-chlorophenyl)ethyl]-5-hydroxy-1H-benzo[g]indole-3-carboxylate
CFAMM00473932 CHEMBL490656 Bioactive SureCN4558554
CFAMM00473939 CHEMBL482849 Bioactive AGN-PC-071TED
CFAMM00473931 CHEMBL519337 Bioactive AGN-PC-071TEC
CFAMM00473949 CHEMBL523292 Bioactive ethyl 2-[(2-chlorophenyl)methyl]-5-hydroxy-1H-benzo[g]indole-3-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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