CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25382
Family Name Peroxisome proliferator-activated receptor gamma ligand AGN-PC-075XR5 family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00474125 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor gamma Binder Superfamily 2
Class Class 4064

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family 5 14
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 1 1
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 2 11
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 7 5
C-C chemokine receptor type 2 ligand AGN-PC-03NT5I family 5 18
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0
Glutamate receptor 2 and Glutamate receptor 4 ligand SureCN828... 1 0


External ID

Functional Category

Molecule Name

CFAMM00474132 CHEMBL372780 Bioactive AGN-PC-075XRA
CFAMM00474125 CHEMBL372639 Bioactive AGN-PC-075XR5
CFAMM00474131 CHEMBL372107 Bioactive AGN-PC-075XQJ
CFAMM00474134 CHEMBL370648 Bioactive AGN-PC-075XRG
CFAMM00474129 CHEMBL426294 Bioactive AGN-PC-075XQK
CFAMM00474128 CHEMBL197636 Bioactive AGN-PC-075XQS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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