CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25443
Family Name Integrin beta-2 and Intercellular adhesion molecule 1 inhibitor (E)-1-(4-acetylpiperazin-1-yl)-3-[3-chloro-4-(1H-indol-5-ylsulfanyl)phenyl]prop-2-en-1-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00474336 Functional Category Bioactive
Superfamily Integrin beta-2 and Intercellular adhesion molecule 1 Binder Superfamily 2
Class Class 1827

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 6
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl... 3 2
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474336 CHEMBL19913 Bioactive (E)-1-(4-acetylpiperazin-1-yl)-3-[3-chloro-4-(1H-indol-5-ylsulfanyl)phenyl]prop-2-en-1-one
CFAMM00474335 CHEMBL277769 Bioactive (E)-1-(4-acetylpiperazin-1-yl)-3-[3-chloro-4-[3-[(dimethylamino)methyl]-1-ethylindol-7-yl]sulfanylphenyl]prop-2-en-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26223 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543