CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM255
Family Name D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-PC-074V7E family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00309541 Functional Category Bioactive
Superfamily D(4) dopamine receptor and D(2) dopamine receptor Binder Superfamily 2
Class Class 2417

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 6
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Translocator protein inhibitor N-methyl-2-[2-oxo-5-[4-(trifluo... 9 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 3
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00309541 CHEMBL106208 Bioactive AGN-PC-074V7E

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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