CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25502
Family Name Sodium- and chloride-dependent glycine transporter 1 inhibitor AGN-PC-00FEO7 family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00474499 Functional Category Bioactive
Superfamily Sodium- and Glutamate receptor ionotropic, NMDA 2B Binder Superfamily
Class Class 3441

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Nociceptin receptor ligand SureCN8... 7 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Melanocortin receptor 4 ligand 2-amino-N-[(2R)-3-(2,4-dichloro... 5 5
Nociceptin receptor and Mu-type opioid receptor ligand spiropi... 1 0
Sodium- and chloride-dependent glycine transporter 1 and Mu-ty... 2 6
Sodium- and chloride-dependent glycine transporter 1 and Mu-ty... 1 3


External ID

Functional Category

Molecule Name

CFAMM00474499 CHEMBL385360 Bioactive AGN-PC-00FEO7
CFAMM00474498 CHEMBL436295 Bioactive 1-(4-fluorophenyl)-8-[(1R,2R)-2-(4-fluorophenyl)-2-hydroxycyclohexyl]-1,3,8-triazaspiro[4.5]decan-4-one
CFAMM00474497 CHEMBL200883 Bioactive 1-(4-chlorophenyl)-8-[(1R,2R)-2-(4-fluorophenyl)-2-hydroxycyclohexyl]-1,3,8-triazaspiro[4.5]decan-4-one
CFAMM00474496 CHEMBL372567 Bioactive 8-[(1R,2R)-2-(4-chlorophenyl)-2-hydroxycyclohexyl]-1-(4-fluorophenyl)-1,3,8-triazaspiro[4.5]decan-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



82433 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543