CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25510
Family Name Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6-chloro-9-oxo-1,2-dihydropyrrolo[2,1-b]quinazolin-3-ylidene)methyl]phenyl]-3-pyrrolidin-1-ylpropanamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00474516 Functional Category Bioactive with Natural Product
Superfamily Kinesin-like protein KIF11 Inhibitor Ispinesib Superfamily
Class Class 882

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
Histone deacetylase 6 and Histone deacetylase 8 inhibitor (E)-... 2 8
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Delta-type opioid receptor ligand SureCN7549631 family 6 3
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474516 CHEMBL2011196 Bioactive N-[4-[(E)-(6-chloro-9-oxo-1,2-dihydropyrrolo[2,1-b]quinazolin-3-ylidene)methyl]phenyl]-3-pyrrolidin-1-ylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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