CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25516
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 6-(4-chloro-3-ethoxyphenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00474528 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 Binder Superfamily 10
Class Class 3394

Cousin Family NamesSeedsMembers
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Thymidylate synthase inhibitor 3-(methylamino)-5,6-dihydro-4H-... 2 19
Transient receptor potential cation channel subfamily V member... 4 6


External ID

Functional Category

Molecule Name

CFAMM00474527 CHEMBL203042 Bioactive 6-(4-chloro-3-methoxyphenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one
CFAMM00474532 CHEMBL201196 Bioactive 6-(3-chloro-5-methoxyphenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one
CFAMM00474531 CHEMBL202039 Bioactive SureCN4881187
CFAMM00474530 CHEMBL383476 Bioactive 6-(3-butoxy-4-chlorophenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one
CFAMM00474529 CHEMBL202977 Bioactive 6-(2,4-dichloro-5-ethoxyphenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one
CFAMM00474528 CHEMBL201247 Bioactive 6-(4-chloro-3-ethoxyphenyl)-2-methyl-7-propan-2-yl-1H-quinazolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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