CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25531
Family Name Dual specificity mitogen-activated protein kinase kinase 1 inhibitor AGN-PC-02ZSOE family
No. of Seeds 8 No. of Other Members 7
Family Centroid CFAMM00474717 Functional Category Bioactive
Superfamily Dual specificity mitogen-activated protein kinase kinase 1 and Cruzipain Binder Superfamily
Class Class 4707

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor Birb 796 Family 20 43
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... 2 1
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 7 5
Dual specificity mitogen-activated protein kinase kinase 1 inh... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474720 CHEMBL369992 Bioactive AGN-PC-02ZSLM
CFAMM00474713 CHEMBL202177 Bioactive AGN-PC-02ZSOB
CFAMM00474717 CHEMBL204535 Bioactive AGN-PC-02ZSOE
CFAMM00474710 CHEMBL201819 Bioactive AGN-PC-03LJVL
CFAMM00474716 CHEMBL414856 Bioactive AGN-PC-02ZSLS
CFAMM00474715 CHEMBL202356 Bioactive AGN-PC-02ZSLO
CFAMM00474721 CHEMBL201389 Bioactive AGN-PC-02ZSRY
CFAMM00474714 CHEMBL265786 Bioactive AGN-PC-02ZSO9

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543