CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25539
Family Name Bromodomain-containing protein 4 and Bromodomain-containing protein 3 inhibitor 1300031-49-5 family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00474785 Functional Category Bioactive
Superfamily Neprilysin and Leukotriene A-4 hydrolase Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Platelet-activating factor receptor ligand SureCN7497229 family 4 2
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3


External ID

Functional Category

Molecule Name

CFAMM00474787 CHEMBL2017281 Bioactive 7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-4-(quinolin-8-ylamino)quinoline-3-carboxamide
CFAMM00474779 CHEMBL2436012 Bioactive 7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-3-[(1R)-1-pyridin-2-ylethyl]-1H-imidazo[4,5-c]quinolin-2-one
CFAMM00474785 CHEMBL2017291 Bioactive 1300031-49-5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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