CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2554
Family Name Transient receptor potential cation channel subfamily V member 1 ligand SureCN6377282 family
No. of Seeds 3 No. of Other Members 18
Family Centroid CFAMM00335318 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 and Cannabinoid receptor 2 Binder Superfamily
Class Class 2351

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Renin Inhibitor Aliskiren Family 28 107
Zucapsacin family 7 177
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand DA-5018 Family 14 73
D(3) dopamine receptor Ligand U-99194A Family 7 33
Ivabradine family 1 11
Ceramide glucosyltransferase Inhibitor Eliglustat Tartrate Family 3 2
Vasopeptidase Inhibitor Fasidotril Family 3 7
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Tubulin beta chain Inhibitor 6-ile-ustiloxin Family 4 3
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 5 2
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 6
Transient receptor potential cation channel subfamily V member... 4 40
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Pol polyprotein inhibitor AC1LA3AI family 5 9
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Cathepsin K inhibitor (2S)-2-[[2-(3,4-dimethoxyphenyl)acetyl]a... 1 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 5
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 4 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
Calpain-1 catalytic subunit inhibitor (2E)-2-[(3,4-dihydroxyph... 4 0
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor 2-(3-chl... 2 0
Chymase and Chymotrypsinogen A inhibitor N-[(2S)-4-chloro-3-ox... 1 0
Putative NP ZINC04041531 Family 40 0
NP (z)-n-((4-(3,4-dimethoxyphenyl)tetrahydro-2h-pyran-4-yl)met... 3 2
3-benzazepin-2-one NP 7,8-dimethoxy-1h-benzo[d]azepin-2(3h)-on... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335330 CHEMBL1277670 Bioactive AGN-PC-08909L
CFAMM00335318 CHEMBL1277576 Bioactive SureCN6377282
CFAMM00335316 CHEMBL1277669 Bioactive AGN-PC-09M7UQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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