CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25544
Family Name Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlorophenyl)-N-[2-[4-[(2-hydroxyacetyl)amino]piperidin-1-yl]-4-methylquinazolin-6-yl]prop-2-enamide family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00474825 Functional Category Bioactive
Superfamily Bacterial outer membrane Inhibitor HKI-9924129 Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
RAC-gamma serine/threonine-protein kinase Inhibitor GDC-0068 F... 20 29
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(4-chlo... 11 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 0
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 2 0
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 6 0
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-(4-cy... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474828 CHEMBL2017757 Bioactive (E)-3-(4-chlorophenyl)-N-[2-[4-(methanesulfonamido)piperidin-1-yl]-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474825 CHEMBL2017759 Bioactive (E)-3-(4-chlorophenyl)-N-[2-[4-[(2-hydroxyacetyl)amino]piperidin-1-yl]-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474824 CHEMBL2017589 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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