CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25545
Family Name Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlorophenyl)-N-[2-(4-hydroxy-4-propylpiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00474837 Functional Category Bioactive
Superfamily Bacterial outer membrane Inhibitor HKI-9924129 Superfamily
Class Class 1053

Cousin Family NamesSeedsMembers
RAC-gamma serine/threonine-protein kinase Inhibitor GDC-0068 F... 20 29
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(4-chlo... 11 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 0
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 2 0
Melanin-concentrating hormone receptor 1 ligand (E)-3-(4-chlor... 3 7
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-(4-cy... 2 0


External ID

Functional Category

Molecule Name

CFAMM00474838 CHEMBL2017602 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-cyclobutyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474837 CHEMBL2017604 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-hydroxy-4-propylpiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474836 CHEMBL2017606 Bioactive (E)-3-(4-chlorophenyl)-N-[2-[4-hydroxy-4-(2-oxopropyl)piperidin-1-yl]-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474834 CHEMBL2017593 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-cyclopropyl-4-hydroxypiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474840 CHEMBL2017601 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-hydroxy-4-phenylpiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide
CFAMM00474839 CHEMBL2017603 Bioactive (E)-3-(4-chlorophenyl)-N-[2-(4-hydroxy-4-propan-2-ylpiperidin-1-yl)-4-methylquinazolin-6-yl]prop-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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