CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25563
Family Name Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00BRDD family
No. of Seeds 5 No. of Other Members 14
Family Centroid CFAMM00474933 Functional Category Bioactive with Natural Product
Superfamily Peptidyl-prolyl cis-trans isomerase FKBP1A Binder Superfamily
Class Class 2276

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Mu-type opioid receptor ligand 3-[(3R,4R)-1-[(2,4-dimethoxyphe... 2 4
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 5 7
Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(... 3 36
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 1 5
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 1 1
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Cyclic az... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 1
Stilbenes Metabolite (Z)-Narceine imide Family 1 1
Putative NP ZINC20113153 Family 20 0
NP (e)-4-methoxy-6,6-dimethyl-5-(2-oxo-4-(2,6,6-trimethylcyclo... 131 0
NP ((1r,4as,8as)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)octahydr... 3 3
Putative NP ZINC08791780 Family 3 0
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474925 CHEMBL202048 Bioactive Tetracyclic aza-amide, 6b
CFAMM00474931 CHEMBL202102 Bioactive AGN-PC-00BMNQ
CFAMM00474923 CHEMBL202227 Bioactive Tetracyclic aza-amide, 6e
CFAMM00474922 CHEMBL201849 Bioactive Tetracyclic aza-amide, 6f
CFAMM00474933 CHEMBL201850 Bioactive AGN-PC-00BRDD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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