CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25569
Family Name Cytochrome P450 2C19 and Cytochrome P450 1A2 inhibitor 2-heptylsulfanyl-6-methoxy-1H-benzimidazole family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00474956 Functional Category Bioactive
Superfamily Cruzipain Inhibitor Triclabendazole Superfamily
Class Class 420

Cousin Family NamesSeedsMembers
Potassium-transporting ATPase alpha chain 1 Inhibitor Rabepraz... 4 113
Histamine H1 receptor Ligand Astemizole Family 7 240
Potassium-transporting ATPase alpha chain 1 Inhibitor Pantopra... 1 3
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[5-chloro-2-[(6-m... 1 7
Methionine aminopeptidase 2 inhibitor SureCN5376830 family 2 1
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 4
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1H-benzimidaz... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00474957 CHEMBL2018909 Bioactive 6-methoxy-2-(2-methylpropylsulfanyl)-1H-benzimidazole
CFAMM00474956 CHEMBL2018908 Bioactive 2-heptylsulfanyl-6-methoxy-1H-benzimidazole
CFAMM00474952 CHEMBL488400 Bioactive AGN-PC-077RWQ
CFAMM00474962 CHEMBL2018920 Bioactive 2-[(4-bromophenyl)methylsulfanyl]-6-methoxy-1H-benzimidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543