CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25589
Family Name Acetylcholinesterase and Butyrylcholinesterase inhibitor 5-amino-7-prop-2-ynyl-2-pyrrolidin-1-yl-8,9-dihydro-6H-pyrido[4,3-b][1,8]naphthyridine-3-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00475047 Functional Category Bioactive
Superfamily Acetylcholinesterase and Butyrylcholinesterase inhibitor 5-amino-7-prop-2-ynyl-2-pyrrolidin-1-yl-8,9-dihydro-6H-pyrido[4,3-b][1,8]naphthyridine-3-carbonitrile Superfamily
Class Class 1373

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Cathepsin K and Potassium voltage-gated channel subfamily H me... 3 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475047 CHEMBL2022933 Bioactive 5-amino-7-prop-2-ynyl-2-pyrrolidin-1-yl-8,9-dihydro-6H-pyrido[4,3-b][1,8]naphthyridine-3-carbonitrile
CFAMM00475046 CHEMBL2022934 Bioactive 5-amino-2-piperidin-1-yl-7-prop-2-ynyl-8,9-dihydro-6H-pyrido[4,3-b][1,8]naphthyridine-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27751 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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