CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25596
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1-(cyclohexylmethyl)-2-oxo-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonyl]amino]benzoic acid family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00475078 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 102
Class Class 3542

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Intedanib family 7 54
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
New permeability pathways Inhibitor 5-nitro-2-(3-phenylpropyla... 1 13
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Beta-secretase 1 Inhibitor KMI-538 Family 4 20
Bifunctional epoxide hydrolase 2 Inhibitor 4-(3-adamantan-1-yl... 3 12
Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(... 2 7
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (2S)-... 3 7
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Dihydrofolate reductase inhibitor AGN-PC-073POJ family 1 0
Retinoic acid receptor beta and Retinoic acid receptor gamma l... 4 7
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 1 0
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 1
Putative NP ZINC12659473 Family 5 0
Putative NP ZINC32123992 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475078 CHEMBL2023574 Bioactive 4-[[1-(cyclohexylmethyl)-2-oxo-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonyl]amino]benzoic acid
CFAMM00475076 CHEMBL64955 Bioactive AGN-PC-074D2C

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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