CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25608
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(1H-indol-7-yl)urea family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00475103 Functional Category Bioactive
Superfamily and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 1116

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Transient receptor potential cation channel subfamily V member... 15 158
D(4) dopamine receptor Ligand L-745,870 Family 30 205
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloro-4-fl... 6 7
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chlo... 1 4
P2X purinoceptor 7 inhibitor N-[1-[(Z)-[(cyanoamino)-(quinolin... 3 3
Sterol O-acyltransferase 1 inhibitor SureCN7073167 family 4 2
Reverse transcriptase/RNaseH inhibitor (4s)-6-chloro-4-cyclopr... 5 3


External ID

Functional Category

Molecule Name

CFAMM00475104 CHEMBL2024659 Bioactive 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(1H-indol-4-yl)urea
CFAMM00475103 CHEMBL2024657 Bioactive 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(1H-indol-7-yl)urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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