CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25609
Family Name Suppressor of tumorigenicity 14 protein and Prothrombin inhibitor 1-[(2S)-3-(3-carbamimidoylphenyl)-2-[(9,10-dioxo-4a,9a-dihydroanthracen-2-yl)sulfonylamino]propanoyl]-N-[2-(diaminomethylideneamino)ethyl]piperidine-4-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00475106 Functional Category Bioactive
Superfamily Prothrombin and Trypsin-1 Binder Superfamily 7
Class Class 1635

Cousin Family NamesSeedsMembers
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Cationic trypsin inhibitor 2-[butyl-[(2S)-4-[[... 7 32
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Suppressor of tumorigenicity 14 protein and Plasminogen inhibi... 10 15
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0


External ID

Functional Category

Molecule Name

CFAMM00475105 CHEMBL202484 Bioactive 3-[(2S)-2-[(9,10-dioxo-4a,9a-dihydroanthracen-2-yl)sulfonylamino]-3-oxo-3-(4-propanoylpiperazin-1-yl)propyl]benzenecarboximidamide
CFAMM00475108 CHEMBL438434 Bioactive 3-[(2S)-3-[4-[3-(diaminomethylideneamino)propanoyl]piperazin-1-yl]-2-[(9,10-dioxo-4a,9a-dihydroanthracen-2-yl)sulfonylamino]-3-oxopropyl]benzenecarboximidamide
CFAMM00475107 CHEMBL540713 Bioactive N-(2-aminoethyl)-1-[(2S)-3-(3-carbamimidoylphenyl)-2-[(9,10-dioxo-4a,9a-dihydroanthracen-2-yl)sulfonylamino]propanoyl]piperidine-4-carboxamide
CFAMM00475106 CHEMBL377361 Bioactive 1-[(2S)-3-(3-carbamimidoylphenyl)-2-[(9,10-dioxo-4a,9a-dihydroanthracen-2-yl)sulfonylamino]propanoyl]-N-[2-(diaminomethylideneamino)ethyl]piperidine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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