CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25615
Family Name Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor SureCN6282968 family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00475125 Functional Category Bioactive
Superfamily Cyclooxygenase 2 and Glucose-dependent insulinotropic receptor Binder Superfamily
Class Class 3175

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 9
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor 2-... 2 10
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Prostaglandin G/H synthase 2 and Cyclooxygenase 2 inhibitor Su... 2 6
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor AG... 1 2


External ID

Functional Category

Molecule Name

CFAMM00475130 CHEMBL413045 Bioactive 5-(3-methylbutan-2-yloxy)-1-(5-methylsulfonylpyridin-2-yl)-3-(trifluoromethyl)pyrazole-4-carbonitrile
CFAMM00475122 CHEMBL202856 Bioactive 5-(2,3-dimethylphenoxy)-1-(5-methylsulfonylpyridin-2-yl)-3-(trifluoromethyl)pyrazole-4-carbonitrile
CFAMM00475126 CHEMBL381716 Bioactive 5-(cyclopentylmethoxy)-1-(5-methylsulfonylpyridin-2-yl)-3-(trifluoromethyl)pyrazole-4-carbonitrile
CFAMM00475132 CHEMBL426117 Bioactive AGN-PC-075ZZX
CFAMM00475125 CHEMBL377499 Bioactive SureCN6282968
CFAMM00475131 CHEMBL204859 Bioactive AGN-PC-075ZZW
CFAMM00475124 CHEMBL381304 Bioactive AGN-PC-075ZY5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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