CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25618
Family Name Malonyl-CoA decarboxylase, mitochondrial inhibitor N-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide family
No. of Seeds 9 No. of Other Members 5
Family Centroid CFAMM00475151 Functional Category Bioactive
Superfamily Acetylcholinesterase and Malonyl-CoA decarboxylase, mitochondrial Binder Superfamily
Class Class 4259

Cousin Family NamesSeedsMembers
Oxysterols receptor LXR Ligand T0901317 Family 13 68
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 8
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 19
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 1 5
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 1


External ID

Functional Category

Molecule Name

CFAMM00475149 CHEMBL205719 Bioactive AGN-PC-00DIPN
CFAMM00475142 CHEMBL203790 Bioactive N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-pentylmorpholine-4-carboxamide
CFAMM00475140 CHEMBL203871 Bioactive AGN-PC-00E2RB
CFAMM00475146 CHEMBL205932 Bioactive N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-propylmorpholine-4-carboxamide
CFAMM00475145 CHEMBL205117 Bioactive N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2-phenylethyl)morpholine-4-carboxamide
CFAMM00475151 CHEMBL202905 Bioactive N-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
CFAMM00475144 CHEMBL380746 Bioactive N-(3-cyanopropyl)-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
CFAMM00475150 CHEMBL381564 Bioactive N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-hexylmorpholine-4-carboxamide
CFAMM00475143 CHEMBL205931 Bioactive AGN-PC-00CX0R

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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