CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25645
Family Name Glucocorticoid receptor and Mineralocorticoid receptor ligand 2-[(3,5-dichlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00475288 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Mineralocorticoid receptor Binder Superfamily 4
Class Class 5934

Cousin Family NamesSeedsMembers
Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Androgen receptor Ligand 2'-hydroxy-3-methoxy-biphenyl-4-carbo... 2 13
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475298 CHEMBL237807 Bioactive 2-[(2,3-dichlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
CFAMM00475291 CHEMBL237377 Bioactive 2-[(2,5-dichlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
CFAMM00475290 CHEMBL392568 Bioactive 2-[(2,4-dichlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
CFAMM00475288 CHEMBL235480 Bioactive 2-[(3,5-dichlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
CFAMM00475293 CHEMBL203151 Bioactive (2S)-2-[(4-chlorophenyl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
CFAMM00475299 CHEMBL392499 Bioactive SureCN5527769

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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