CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25654
Family Name Potassium voltage-gated channel subfamily H member 2 ligand 1-[1-[6,6-bis(4-fluorophenyl)hexyl]pyrrolidin-3-yl]-N-[(3,4,5-trimethoxyphenyl)methyl]methanamine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00475311 Functional Category Bioactive
Superfamily Muscleblind-like protein 1 and Cellular tumor antigen p53 Binder Superfamily 5
Class Class 332

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Tubulin beta chain Inhibitor Colchinol Family 3 109
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2


External ID

Functional Category

Molecule Name

CFAMM00475312 CHEMBL2031998 Bioactive 6,6-bis(4-fluorophenyl)-N-[[1-[(3,4,5-trimethoxyphenyl)methyl]pyrrolidin-3-yl]methyl]hexan-1-amine
CFAMM00475311 CHEMBL2031983 Bioactive 1-[1-[6,6-bis(4-fluorophenyl)hexyl]pyrrolidin-3-yl]-N-[(3,4,5-trimethoxyphenyl)methyl]methanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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