CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2566
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-073M7W family
No. of Seeds 19 No. of Other Members 2
Family Centroid CFAMM00335467 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta Inhibitor A-313326 Superfamily
Class Class 2754

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor Cp-609,75... 2 11
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Extracellular calcium-sensing receptor ligand SureCN2972008 fa... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 21 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335461 CHEMBL434396 Bioactive AGN-PC-073MI9
CFAMM00335474 CHEMBL38616 Bioactive AGN-PC-073MIT
CFAMM00335467 CHEMBL39117 Bioactive AGN-PC-073M7W
CFAMM00335460 CHEMBL38438 Bioactive AGN-PC-073MHV
CFAMM00335473 CHEMBL288901 Bioactive AGN-PC-073MHY
CFAMM00335466 CHEMBL39805 Bioactive AGN-PC-073M8B
CFAMM00335472 CHEMBL288838 Bioactive AGN-PC-073MFA
CFAMM00335465 CHEMBL185058 Bioactive AGN-PC-075G3A
CFAMM00335471 CHEMBL38567 Bioactive AGN-PC-073MDV
CFAMM00335464 CHEMBL41682 Bioactive AGN-PC-073MLV
CFAMM00335470 CHEMBL41268 Bioactive AGN-PC-073MH5
CFAMM00335463 CHEMBL290760 Bioactive 5-(3-chlorophenyl)-6-[[(4-cyanophenyl)-(3-methylimidazol-4-yl)methoxy]methyl]-2-(4-methylpiperazin-1-yl)pyridine-3-carbonitrile
CFAMM00335469 CHEMBL288046 Bioactive AGN-PC-073M7U

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26238 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543