CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25662
Family Name TGF-beta receptor type-1 ligand Methyl 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)benzoate family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00475335 Functional Category Bioactive
Superfamily TGF-beta receptor type-1 and Nuclear receptor ROR-gamma Binder Superfamily
Class Class 3380

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 5 10
Proteinase-activated receptor 4 Ligand Ethyl 4-(1-benzyl-1h-in... 1 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
MAP kinase-activated protein kinase 2 inhibitor SureCN14188371... 1 0
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475335 CHEMBL203436 Bioactive Methyl 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26194 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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