CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25683
Family Name Caspase-3 inhibitor Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1,3,4-trioxo-5-isoquinolinyl)- family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00475390 Functional Category Bioactive
Superfamily MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-2,3-dione Superfamily
Class Class 2203

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-... 1 4
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Telomerase reverse transcriptase Inhibitor 2,7-bis[2-(piperidi... 6 8
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 11
Vascular endothelial growth factor receptor 2 ligand SureCN578... 1 2
Caspase-3 and Caspase-7 inhibitor AGN-PC-00BUR6 family 2 1
Caspase-3 inhibitor SureCN12857739 family 1 1
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475393 CHEMBL204645 Bioactive AGN-PC-00BPX4
CFAMM00475390 CHEMBL203971 Bioactive Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1,3,4-trioxo-5-isoquinolinyl)-

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46270 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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