CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25690
Family Name Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydrogenase 2 inhibitor N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide family
No. of Seeds 15 No. of Other Members 3
Family Centroid CFAMM00464296 Functional Category Bioactive
Superfamily DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenesulfonic Acid Superfamily
Class Class 1407

Cousin Family NamesSeedsMembers
DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenes... 1 19
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4'-am... 3 17
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 3 10
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 2 0
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 1 1
Protein arginine N-methyltransferase 1 and RmtA inhibitor 134-... 1 4


External ID

Functional Category

Molecule Name

CFAMM00475420 CHEMBL2041365 Bioactive N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-4-nitrobenzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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