CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25696
Family Name Serine/threonine-protein kinase Nek2 and Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0BMUNC family
No. of Seeds 9 No. of Other Members 4
Family Centroid CFAMM00475444 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Nek2 and Serine/threonine-protein kinase PLK1 Binder Superfamily
Class Class 513

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 inhibitor 2-(4-methoxyphe... 6 7
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475437 CHEMBL602931 Bioactive AGN-PC-076XGI
CFAMM00475436 CHEMBL2042035 Bioactive 4-[2-amino-5-[5-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide
CFAMM00475442 CHEMBL2042135 Bioactive 4-[2-amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(Z,2R)-5,5,5-trifluoropent-3-en-2-yl]oxybenzamide
CFAMM00475435 CHEMBL2042036 Bioactive 4-[2-amino-5-[5-[(dimethylamino)methyl]-4-methylthiophen-2-yl]pyridin-3-yl]-2-[1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide
CFAMM00475441 CHEMBL2042136 Bioactive 4-[2-amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide
CFAMM00475434 CHEMBL2042037 Bioactive 4-[2-amino-5-[5-[(dimethylamino)methyl]-3-methylthiophen-2-yl]pyridin-3-yl]-2-[1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide
CFAMM00475440 CHEMBL2042038 Bioactive 4-[2-amino-5-[5-(piperidin-1-ylmethyl)thiophen-2-yl]pyridin-3-yl]-2-[1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide
CFAMM00475445 CHEMBL2042041 Bioactive 4-[2-amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(Z)-5,5,5-trifluoropent-3-en-2-yl]oxybenzamide
CFAMM00475444 CHEMBL2042040 Bioactive AGN-PC-0BMUNC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27027 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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