CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25708
Family Name Caspase-3 inhibitor AGN-PC-00ELYM family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00475544 Functional Category Bioactive
Superfamily Caspase-3 and Beta-lactamase Binder Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Dual specificity mitogen-activated protein kinase kinase 1 inh... 9 1
Major prion protein and Microtubule-associated protein tau inh... 2 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475542 CHEMBL206607 Bioactive AGN-PC-00EFTV
CFAMM00475544 CHEMBL204529 Bioactive AGN-PC-00ELYM
CFAMM00475543 CHEMBL206844 Bioactive AGN-PC-00E28N

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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