CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2572
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-075KFA family
No. of Seeds 21 No. of Other Members 0
Family Centroid CFAMM00335592 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 5
Class Class 2754

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor Cp-609,75... 2 11
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 19 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335590 CHEMBL128501 Bioactive AGN-PC-075KEY
CFAMM00335603 CHEMBL128897 Bioactive 6-[[(4-cyanophenyl)-(3-methylimidazol-4-yl)methoxy]methyl]-5-(2,5-dichlorophenyl)-1-methyl-2-oxopyridine-3-carbonitrile
CFAMM00335596 CHEMBL336569 Bioactive AGN-PC-075KFQ
CFAMM00335602 CHEMBL128309 Bioactive SureCN5099735
CFAMM00335595 CHEMBL128760 Bioactive AGN-PC-075KEW
CFAMM00335601 CHEMBL131612 Bioactive AGN-PC-075K7X
CFAMM00335594 CHEMBL129685 Bioactive AGN-PC-075KFO
CFAMM00335600 CHEMBL365269 Bioactive 3-[[4-(3-chlorophenyl)-5-[[(4-cyanophenyl)-(3-methylimidazol-4-yl)methoxy]methyl]-2-oxopyridin-1-yl]methyl]benzonitrile
CFAMM00335593 CHEMBL363518 Bioactive AGN-PC-075F9Q
CFAMM00335599 CHEMBL131609 Bioactive AGN-PC-075KCF
CFAMM00335592 CHEMBL128282 Bioactive AGN-PC-075KFA
CFAMM00335605 CHEMBL131081 Bioactive SureCN5099631
CFAMM00335598 CHEMBL131108 Bioactive SureCN5940417
CFAMM00335591 CHEMBL128571 Bioactive AGN-PC-075KFW
CFAMM00335604 CHEMBL131116 Bioactive AGN-PC-075KFM
CFAMM00335597 CHEMBL132337 Bioactive AGN-PC-075KC6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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