CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25720
Family Name Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial inhibitor (3S)-3-amino-8-fluoro-1-hydroxy-3,4-dihydroquinolin-2-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00475580 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolinone Superfamily
Class Class 67

Cousin Family NamesSeedsMembers
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 3
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Chitin synthase 1 inhibitor AC1O53V7 family 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475577 CHEMBL2049095 Bioactive (3S)-3-amino-1-hydroxy-6-(trifluoromethyl)-3,4-dihydroquinolin-2-one
CFAMM00475580 CHEMBL2047856 Bioactive (3S)-3-amino-8-fluoro-1-hydroxy-3,4-dihydroquinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26854 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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