CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2573
Family Name Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acid family
No. of Seeds 7 No. of Other Members 23
Family Centroid CFAMM00335612 Functional Category Bioactive
Superfamily Angiotensin-converting enzyme and Neprilysin Binder Superfamily
Class Class 3583

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
D(4) dopamine receptor and D(2) dopamine receptor ligand methy... 2 11
Angiotensin-converting enzyme inhibitor AGN-PC-074KD3 family 2 0
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2... 2 3
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Granzyme B and Caspase-3 inhibitor CHEMBL304368 family 2 1
Angiotensin-converting enzyme inhibitor 89177-63-9 family 2 0
Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335609 CHEMBL611148 Bioactive (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00335634 CHEMBL611149 Bioactive (2R)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00335627 CHEMBL75752 Bioactive (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00335633 CHEMBL610903 Bioactive (2S)-1-(3-sulfanylpropanoyl)-2,3-dihydroindole-2-carboxylic acid
CFAMM00335612 CHEMBL128287 Bioactive (2S)-1-[(2S)-2-sulfanylpropanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00335611 CHEMBL283586 Bioactive AGN-PC-01YQMX
CFAMM00335618 CHEMBL22198 Bioactive AGN-PC-076HT5

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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