CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25804
Family Name Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-03LEDF family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00475935 Functional Category Bioactive
Superfamily Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase ITK/TSK Binder Superfamily
Class Class 2633

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Arachidonate 5-lipoxygenase Inhibitor N-(thiazol-2-yl)benzamid... 3 53
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Acyl-CoA desaturase and Acyl-CoA desaturase 1 Inhibitor MF-152... 2 1
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-(4... 3 9
Cellular tumor antigen p53 inhibitor CHEMBL1395891 family 1 6
Aurora kinase A inhibitor AGN-PC-09QJBI family 1 2
Neuropeptide Y receptor type 5 ligand 3-[[5-(2-methylbenzoyl)-... 2 8
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
MAP kinase-activated protein kinase 2 inhibitor 2-[(4,4-dimeth... 11 11
High affinity nerve growth factor receptor and Hepatocyte grow... 6 8
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Tyrosine-protein kinase ABL1 inhibitor AGN-PC-04SU6B family 2 3
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-02WPOZ family 1 1
Glucokinase inhibitor AGN-PC-078XNA family 2 9
Glucokinase inhibitor (2S)-3-cyclohexyl-2-(7-ethylsulfonyl-4-o... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00475939 CHEMBL210243 Bioactive AGN-PC-03LEDH
CFAMM00475936 CHEMBL207329 Bioactive AGN-PC-02WPP7
CFAMM00475935 CHEMBL206905 Bioactive AGN-PC-03LEDF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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