CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25829
Family Name Metabotropic glutamate receptor 5 ligand N-[2-[(3-chlorophenyl)methoxy]-6-methylpyridin-4-yl]-N-methylpyrimidin-5-amine family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00476144 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1h-benzoimidazol-4-yloxy)-ethyl]-benzyl-amine Superfamily
Class Class 2014

Cousin Family NamesSeedsMembers
SB1518 family 7 103
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Deoxycytidine kinase inhibitor 2-[1-[6-(2-chlorophenoxy)pyrimi... 2 3
Heat shock protein HSP 90-alpha inhibitor 3-[2-amino-4-chloro-... 7 2
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Transient receptor potential cation channel subfamily V member... 2 4
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Dihydrofolate reductase inhibitor AGN-PC-001U7R family 3 0
Sodium channel protein type 5 subunit alpha and Sodium channel... 15 8
Protein kinase C alpha type inhibitor AGN-PC-02T9JO family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00476144 CHEMBL207097 Bioactive N-[2-[(3-chlorophenyl)methoxy]-6-methylpyridin-4-yl]-N-methylpyrimidin-5-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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