CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25844
Family Name C-X-C chemokine receptor type 2 ligand (2S)-2-[[6-butyl-2-(4-methylimidazol-1-yl)pyrimidin-4-yl]amino]-N-(3-ethoxypropyl)-4-methylpentanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00476184 Functional Category Bioactive
Superfamily High affinity cAMP-specific and C-X-C chemokine receptor type 2 Binder Superfamily
Class Class 5633

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Translocator protein Inhibitor Emapunil Family 7 89
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(5-methylbenzimidazol-1... 5 27
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 0
Serine/threonine-protein kinase PLK2 and Serine/threonine-prot... 1 2
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 3 0


External ID

Functional Category

Molecule Name

CFAMM00476184 CHEMBL207276 Bioactive (2S)-2-[[6-butyl-2-(4-methylimidazol-1-yl)pyrimidin-4-yl]amino]-N-(3-ethoxypropyl)-4-methylpentanamide
CFAMM00476182 CHEMBL382377 Bioactive (2S)-2-[[6-butyl-2-(4-tert-butylimidazol-1-yl)pyrimidin-4-yl]amino]-N-(3-ethoxypropyl)-4-methylpentanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55978 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543