CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25867
Family Name Amiloride-sensitive sodium channel subunit alpha ligand AGN-PC-00BG6O family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00476253 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 3 and Amiloride-sensitive sodium channel subunit alpha Binder Superfamily
Class Class 1165

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A2a and Adenosine receptor A2b Ligand Allox... 1 10
Metabotropic glutamate receptor 5 ligand SureCN3866791 family 2 10
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 11 1
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 2 0
Amiloride-sensitive sodium channel subunit alpha ligand AGN-PC... 1 0


External ID

Functional Category

Molecule Name

CFAMM00476250 CHEMBL211664 Bioactive AGN-PC-00DC8F
CFAMM00476256 CHEMBL208620 Bioactive AGN-PC-00A9CF
CFAMM00476255 CHEMBL212410 Bioactive 3,5-diamino-N-[N'-[4-(4-aminophenyl)butyl]carbamimidoyl]-6-chloropyrazine-2-carboxamide
CFAMM00476254 CHEMBL211611 Bioactive AGN-PC-00EQGS
CFAMM00476253 CHEMBL209659 Bioactive AGN-PC-00BG6O
CFAMM00476252 CHEMBL377239 Bioactive AGN-PC-00DMTD

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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