CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25868
Family Name Protein-glutamine gamma-glutamyltransferase 2 and Coagulation factor XIII A chain inhibitor (4-fluorophenyl)methyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate family
No. of Seeds 7 No. of Other Members 17
Family Centroid CFAMM00476259 Functional Category Bioactive
Superfamily D(4) dopamine receptor Ligand Sonepiprazole Superfamily
Class Class 1104

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand Sonepiprazole Family 2 6
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 7
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BL6AB family 1 3
Prothrombin and Trypsin-1 inhibitor benzyl N-[(2R)-1-[4-[(diam... 2 0


External ID

Functional Category

Molecule Name

CFAMM00476265 CHEMBL2086508 Bioactive (3,5-difluorophenyl)methyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate
CFAMM00476258 CHEMBL2089389 Bioactive benzyl (3R)-3-[[4-(prop-2-enoylamino)phenyl]sulfonylamino]pyrrolidine-1-carboxylate
CFAMM00476264 CHEMBL2086509 Bioactive (2-chlorophenyl)methyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate
CFAMM00476261 CHEMBL2086505 Bioactive benzyl 4-[4-(prop-2-enoylamino)-2-(trifluoromethyl)phenyl]sulfonylpiperazine-1-carboxylate
CFAMM00476260 CHEMBL2086506 Bioactive (2,3-difluorophenyl)methyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate
CFAMM00476277 CHEMBL2086513 Bioactive naphthalen-1-ylmethyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate
CFAMM00476259 CHEMBL2086507 Bioactive (4-fluorophenyl)methyl 4-[4-(prop-2-enoylamino)phenyl]sulfonylpiperazine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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