CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25870
Family Name Protein-glutamine gamma-glutamyltransferase 2 and Coagulation factor XIII A chain inhibitor N-[4-[4-(3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-2-carbonyl)piperazin-1-yl]sulfonylphenyl]prop-2-enamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00476307 Functional Category Bioactive with Natural Product
Superfamily Coagulation factor XIII A chain and Protein-glutamine gamma-glutamyltransferase 2 Binder Superfamily
Class Class 3199

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor ST510... 7 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
Coagulation factor XIII A chain and Protein-glutamine gamma-gl... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00476307 CHEMBL2086523 Bioactive N-[4-[4-(3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-2-carbonyl)piperazin-1-yl]sulfonylphenyl]prop-2-enamide
CFAMM00476309 CHEMBL2086526 Bioactive N-[4-[4-(4,4-difluoropiperidine-1-carbonyl)piperazin-1-yl]sulfonylphenyl]prop-2-enamide
CFAMM00476308 CHEMBL2086524 Bioactive N-[4-[4-(3,4,4a,5,6,7,8,8a-octahydro-2H-quinoline-1-carbonyl)piperazin-1-yl]sulfonylphenyl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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