CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25873
Family Name Protein-glutamine gamma-glutamyltransferase 2 and Coagulation factor XIII A chain inhibitor benzyl 4-[6-(prop-2-enoylamino)pyridin-3-yl]sulfonylpiperazine-1-carboxylate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00476317 Functional Category Bioactive
Superfamily Coagulation factor XIII A chain and Protein-glutamine gamma-glutamyltransferase 2 Binder Superfamily 2
Class Class 3925

Cousin Family NamesSeedsMembers
Neutrophil elastase inhibitor SureCN7284457 family 4 6
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Melanin-concentrating hormone receptor 1 ligand 1-[6-[(3R)-3-a... 1 5
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453479 ... 3 5
Bloom syndrome protein and Nuclear factor NF-kappa-B p105 subu... 1 5
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 1 0


External ID

Functional Category

Molecule Name

CFAMM00476317 CHEMBL2086539 Bioactive benzyl 4-[6-(prop-2-enoylamino)pyridin-3-yl]sulfonylpiperazine-1-carboxylate
CFAMM00476316 CHEMBL2086543 Bioactive benzyl 4-[2-(prop-2-enoylamino)pyrimidin-5-yl]sulfonylpiperazine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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