CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25879
Family Name C-C chemokine receptor type 2 ligand (2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-[2-(dimethylamino)ethylsulfanyl]-2-phenylacetamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00476325 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 173
Class Class 3401

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Substance-P receptor Ligand Orvepitant Family 11 46
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 4
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(3-... 1 7
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Substance-P receptor ligand AGN-PC-075NRR family 2 1
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 5 1
Lysine-specific histone demethylase 1A and Amine oxidase [flav... 2 1
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
C-C chemokine receptor type 2 ligand (2S)-N-[[3,5-bis(trifluor... 1 0
Substance-P receptor ligand AGN-PC-073QYE family 6 11
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3-fluoro-5-(t... 22 27
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
Substance-P receptor and Potassium voltage-gated channel subfa... 5 1
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Kinesin-like protein KIF11 inhibitor 1-[4-[2-aminoethylsulfany... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00476325 CHEMBL208685 Bioactive (2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-[2-(dimethylamino)ethylsulfanyl]-2-phenylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27409 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543