CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2588
Family Name Serine/threonine-protein kinase Chk1 inhibitor 2-(4-methoxyphenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00335770 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Beta-lactamase Binder Superfamily
Class Class 3263

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
Neuropeptides B/W receptor type 1 ligand [4-(1H-benzimidazol-2... 6 4
Neuropeptides B/W receptor type 1 ligand [4-(5-chloropyridin-2... 1 4
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Melanin-concentrating hormone receptor 1 ligand 2-(4-methoxyph... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
Serine/threonine-protein kinase Nek2 and Serine/threonine-prot... 9 4


External ID

Functional Category

Molecule Name

CFAMM00335782 CHEMBL1287865 Bioactive 2-(6-methoxypyridin-3-yl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
CFAMM00335772 CHEMBL1288043 Bioactive 2-(4-phenoxyphenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
CFAMM00335770 CHEMBL1288009 Bioactive 2-(4-methoxyphenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
CFAMM00335778 CHEMBL1287979 Bioactive 2-(3-methoxyphenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
CFAMM00335769 CHEMBL1288193 Bioactive 4-[[(3S)-piperidin-3-yl]amino]-2-[4-(trifluoromethoxy)phenyl]thieno[3,2-c]pyridine-7-carboxamide
CFAMM00335777 CHEMBL1288222 Bioactive 2-(1-benzofuran-2-yl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



57902 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543