CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25911
Family Name Angiopoietin-1 receptor ligand 4-[4-(6-methoxynaphthalen-2-yl)-2-[2-methyl-4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00476696 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Acyl-CoA desaturase Binder Superfamily
Class Class 937

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 3
Renin inhibitor AGN-PC-09M4GD family 3 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 3
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Neuropeptide Y receptor type 5 ligand 6-ethylsulfonyl-2-(4-phe... 4 4
Arachidonate 15-lipoxygenase inhibitor SureCN14288120 family 3 12
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 1
Glucagon receptor ligand SureCN2647807 family 3 7
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
Transitional endoplasmic reticulum ATPase inhibitor 4-[4-[(5-c... 4 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00476696 CHEMBL2096892 Bioactive 4-[4-(6-methoxynaphthalen-2-yl)-2-[2-methyl-4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine
CFAMM00476695 CHEMBL2448122 Bioactive 4-[4-(6-methoxynaphthalen-2-yl)-2-[2-methyl-4-[(S)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine
CFAMM00476688 CHEMBL236716 Bioactive AGN-PC-076B2M
CFAMM00476694 CHEMBL391891 Bioactive AGN-PC-076B2N
CFAMM00476693 CHEMBL236924 Bioactive AGN-PC-076B2P
CFAMM00476692 CHEMBL392332 Bioactive AGN-PC-076B2Q

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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