CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM25923
Family Name N-formyl peptide receptor 2 ligand 1-(1-methyl-3-oxo-5-propan-2-yl-2-quinolin-3-ylpyrazol-4-yl)-3-[4-(trifluoromethyl)phenyl]urea family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00476744 Functional Category Bioactive
Superfamily Cathepsin K and Cathepsin S Binder Superfamily 7
Class Class 147

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
Amg 423 family 7 47
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Urotensin-2 receptor Ligand Palosuran Family 4 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 1 13
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
N-formyl peptide receptor 2 ligand AGN-PC-0763EC family 1 1


External ID

Functional Category

Molecule Name

CFAMM00476744 CHEMBL380389 Bioactive 1-(1-methyl-3-oxo-5-propan-2-yl-2-quinolin-3-ylpyrazol-4-yl)-3-[4-(trifluoromethyl)phenyl]urea
CFAMM00476742 CHEMBL379762 Bioactive AGN-PC-0763EP
CFAMM00476745 CHEMBL210303 Bioactive 1-(4-chlorophenyl)-3-(1-methyl-3-oxo-5-propan-2-yl-2-quinolin-3-ylpyrazol-4-yl)urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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