CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26059
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor 6-(3-methylbut-2-enyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00477344 Functional Category Bioactive
Superfamily Muscleblind-like protein 1 and Beta-lactamase Binder Superfamily 2
Class Class 2589

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Substance-P receptor Ligand TAK-637 Family 18 63
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
MO15-related protein kinase Pfmrk Inhibitor (e)-1-(4-nitro-phe... 2 9
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477344 CHEMBL2158056 Bioactive 6-(3-methylbut-2-enyl)-8-(3-nitrophenyl)pyrido[2,3-d]pyridazin-5-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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