CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2606
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2B ligand SureCN3392243 family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00119834 Functional Category Bioactive
Superfamily adrenergic receptor ligand catecholamine Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Opioid receptor ligand opiate Levorphanol Family 18 537
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Acolbifene family 10 115
CORT-108297 family 46 44
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Acetylcholinesterase and Cholinesterase Inhibitor N,n'-(1',10'... 12 8
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00G... 16 4
Glutamate receptor ionotropic, NMDA 3A and Glutamate receptor ... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Estrogen receptor and Estrogen receptor beta ligand SureCN5681... 7 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
D(1A) dopamine receptor ligand (5S)-5-(4-azidophenyl)-8-iodo-3... 2 0
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 2
Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)... 3 0
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor ligand CHEMBL2367762 family 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
D(4) dopamine receptor ligand AGN-PC-073HVQ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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