CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26067
Family Name Dipeptidyl peptidase 4 inhibitor 7-amino-6-(aminomethyl)-5-(2-methoxyphenyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4-dione family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00477367 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Nuclear receptor ROR-gamma Binder Superfamily
Class Class 1305

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1


External ID

Functional Category

Molecule Name

CFAMM00477368 CHEMBL2159186 Bioactive 7-amino-6-(aminomethyl)-5-(5-fluoro-2-methoxyphenyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4-dione
CFAMM00477367 CHEMBL2159179 Bioactive 7-amino-6-(aminomethyl)-5-(2-methoxyphenyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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